CASP9 Polyclonal Antibody | G-AB-05866

CASP9 Polyclonal Antibody | G-AB-05866 | Gentaur Antibodies

Overview: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly (ADP-ribose) polymerase (PARP) .Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Metabolism

Synonyms: APAF-3, APAF3, Apoptosis related cysteine peptidase, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, CASP-9, CASP9, CASP9, Caspase 9 apoptosis related cysteine peptidase, Caspase 9 Dominant Negative, Caspase 9c, Caspase-9, Caspase-9 subunit p10, ICE LAP6, ICE like apoptotic protease 6, ICE-LAP6, ICE-like apoptotic protease 6, MCH6, PPP1R56, protein phosphatase 1, regulatory subunit 56, RNCASP9

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #:

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human Caspase-9 around the non-phosphorylation site of Thr125.

Clone #:

Conjugation: Unconjugated

Swissprot: P55211

Santa Cruz: sc-22182/sc-8297/sc-8355/sc-7885

Calculated MW: 46 kDa

Observed MW: 46 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

Purification method: Affinity purification

Application: WB, IHC-p, IF, ELISA

Dilution: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CASP9 Polyclonal Antibody DataSheet