Caspase-9 Polyclonal Antibody | G-AB-10163

Caspase-9 Polyclonal Antibody | G-AB-10163 | Gentaur Antibodies

Overview: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Metabolism

Synonyms: CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56, caspase-9, casp9, Caspase 9

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 842

Accession #:

Clonality:

Immunogen: Recombinant protein of human Caspase-9

Clone #:

Conjugation: Unconjugated

Swissprot: P55211

Santa Cruz:

Calculated MW: 17 kDa/30 kDa/36 kDa/46 kDa

Observed MW: 36 kDa/46 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC, IF

Dilution: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Caspase-9 Polyclonal Antibody DataSheet