CAST Polyclonal Antibody | G-AB-09546

CAST Polyclonal Antibody | G-AB-09546 | Gentaur Antibodies

Overview: The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4) , and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Neuroscience

Synonyms: CAST, BS-17, PLACK

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID: 831

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human CAST (NP_001177371.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P20810

Santa Cruz:

Calculated MW: 63 kDa/71- 84 kDa

Observed MW: 120 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC

Dilution: WB 1:500-1:2000 IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CAST Polyclonal Antibody DataSheet