β-catenin Polyclonal Antibody | G-AB-07651

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$281.00 - $387.00
SKU:
G-AB-07651
Availability:
3 to 5 Working Days
Host:
Rabbit
Reactivity:
Human, Mouse, Rat
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β-catenin Polyclonal Antibody | G-AB-07651 | Gentaur Antibodies

Overview: The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs) . AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC) , pilomatrixoma (PTR) , medulloblastoma (MDB) , and ovarian cancer. Alternative splicing results in multiple transcript variants.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Neuroscience, Signal Transduction, Stem Cells

Synonyms: CTNNB, MRD19, armadillo, beta Catenin, CTNNB1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 1499

Accession #:

Clonality:

Immunogen: Recombinant protein of human beta Catenin

Clone #:

Conjugation: Unconjugated

Swissprot: P35222

Santa Cruz:

Calculated MW: 9 kDa/85 kDa

Observed MW: 92 kDa/100 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

β-catenin Polyclonal Antibody DataSheet

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