β-catenin Polyclonal Antibody | G-AB-07651
Gentaur Antibodies
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Gentaur Antibodies
β-catenin Polyclonal Antibody | G-AB-07651
- SKU:
- G-AB-07651
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
β-catenin Polyclonal Antibody | G-AB-07651 | Gentaur Antibodies
Overview: The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs) . AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC) , pilomatrixoma (PTR) , medulloblastoma (MDB) , and ovarian cancer. Alternative splicing results in multiple transcript variants.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cardiovascular, Neuroscience, Signal Transduction, Stem Cells
Synonyms: CTNNB, MRD19, armadillo, beta Catenin, CTNNB1
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID: 1499
Accession #:
Clonality:
Immunogen: Recombinant protein of human beta Catenin
Clone #:
Conjugation: Unconjugated
Swissprot: P35222
Santa Cruz:
Calculated MW: 9 kDa/85 kDa
Observed MW: 92 kDa/100 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB
Dilution: WB 1:500-1:2000
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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