CAV1 Polyclonal Antibody | G-AB-09091

CAV1 Polyclonal Antibody | G-AB-09091 | Gentaur Antibodies

Overview: The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Metabolism, Signal Transduction, Tags & Cell Markers

Synonyms: BSCL3, CGL3, LCCNS, MSTP085, PPH3, VIP21, CAV1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 857

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human CAV1 (NP_001744.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q03135

Santa Cruz:

Calculated MW: 17 kDa/20 kDa

Observed MW: 20 kDa/23 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CAV1 Polyclonal Antibody DataSheet