CCDC181 Polyclonal Antibody | G-AB-06289

CCDC181 Polyclonal Antibody | G-AB-06289 | Gentaur Antibodies

Overview: CCDC181, also known as C1orf114, chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3, 000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf114 gene product has been provisionally designated C1orf114 pending further characterization.

Category Type: Polyclonal Antibody

Research Areas: Cell Biology

Synonyms: C1orf114, CA114, Chromosome 1 open reading frame 114, RP1-206D15.2, Uncharacterized protein C1orf114

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC026073

Clonality: Polyclonal

Immunogen: Fusion protein of human CCDC181

Clone #:

Conjugation: Unconjugated

Swissprot: Q5TID7

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 0.8 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: IHC, ELISA

Dilution: IHC 1:40-1:200, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CCDC181 Polyclonal Antibody DataSheet