CCNH Polyclonal Antibody | G-AB-07280

CCNH Polyclonal Antibody | G-AB-07280 | Gentaur Antibodies

Overview: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK) . This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery. A pseudogene of this gene is found on chromosome 4. Alternate splicing results in multiple transcript variants.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling

Synonyms: CCNH, CAK, CycH, p34, p37, cyclin-H

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID: 902

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human CCNH (NP_001230.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P51946

Santa Cruz:

Calculated MW: 37 kDa

Observed MW: 36 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CCNH Polyclonal Antibody DataSheet