CD284 Polyclonal Antibody | G-AB-05238
- 3 to 5 Working Days
- Human, Rat
CD284 Polyclonal Antibody | G-AB-05238 | Gentaur Antibodies
Overview: TLR4, also named as CD284, belongs to the Toll-like receptor family. TLR4 cooperates with LY96 and CD14 to mediates the innate immune response to bacterial lipopolysaccharide (LPS) . TLR4 acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cardiovascular, Immunology, Microbiology
Synonyms: ARMD10, CD284, CD284 antigen, Homolog of Drosophila toll, hToll, TLR 4, TLR4, TLR4, TOLL, Toll like receptor 4, Toll-like receptor 4
Reactivity: Human, Rat
Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse TLR4
Swissprot: O00206, Q9QUK6, Q9QX05
Concentration: 1.1 mg/mL
Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
Purification method: Affinity purification
Dilution: IHC 1:200-1:800
Storage: Store at -20°C. Avoid freeze / thaw cycles.