CD2AP Polyclonal Antibody | G-AB-03081

CD2AP Polyclonal Antibody | G-AB-03081 | Gentaur Antibodies

Overview: This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.

Category Type: Polyclonal Antibody

Research Areas: Signal Transduction

Synonyms: Adapter protein CMS, AL024079, C78928, Cas ligand with multiple SH3 domains, CD2 associated protein, CD2-associated protein, CD2AP, CD2AP, CMS, Mesenchyme to epithelium transition protein with SH3 domains 1, METS 1, Mets1

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_036252

Clonality: Polyclonal

Immunogen: Synthetic peptide of human CD2AP

Clone #:

Conjugation: Unconjugated

Swissprot: Q9Y5K6

Santa Cruz: sc-8763/sc-34228/sc-8764/sc-9137

Calculated MW: 71 kDa

Observed MW:

Concentration: 0.2 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:1000-1:5000, IHC 1:100-1:300

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CD2AP Polyclonal Antibody DataSheet