CD42b Polyclonal Antibody | G-AB-02528
Gentaur Antibodies
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Gentaur Antibodies
CD42b Polyclonal Antibody | G-AB-02528
- SKU:
- G-AB-02528
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human
CD42b Polyclonal Antibody | G-AB-02528 | Gentaur Antibodies
Overview: Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF) . The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Mutations in this gene result in Bernard-Soulier syndromes and platelet-type von Willebrand disease. The coding region of this gene is known to contain a polymophic variable number tandem repeat (VNTR) domain that is associated with susceptibility to nonarteritic anterior ischemic optic neuropathy.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cardiovascular, Immunology
Synonyms: Antigen CD42b alpha, BDPLT1, BDPLT3, BSS, CD 42b, CD42b alpha, CD42B, CD42b antigen, DBPLT3, GLYCOCALICIN, Glycoprotein Ib (platelet) alpha polypeptide, Glycoprotein Ibalpha, GP Ib alpha, GP1B, GP1BA, GPIb alpha, GPIbA, MGC34595, Platelet glycoprotein Ib alpha chain, Platelet glycoprotein Ib alpha polypeptide, Platelet membrane glycoprotein 1b alpha subunit, VWDP
Reactivity: Human
Host: Rabbit
Isotype: IgG
Gene ID:
Accession #: BC027955
Clonality: Polyclonal
Immunogen: Recombinant protein of human GP1BA
Clone #:
Conjugation: Unconjugated
Swissprot: P07359
Santa Cruz: sc-7070/sc-7071
Calculated MW:
Observed MW:
Concentration: 0.3 mg/mL
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Affinity purification
Application: IHC, ELISA
Dilution: IHC 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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