CD59 Polyclonal Antibody | G-AB-01633

CD59 Polyclonal Antibody | G-AB-01633 | Gentaur Antibodies

Overview: This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte Signal Transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in Signal Transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Immunology, Signal Transduction, Stem Cells

Synonyms: 16.3A5, 1F5, 1F5 antigen, 20 kDa homologous restriction factor, CD 59, CD_antigen=CD59, CD59, CD59 antigen, CD59 antigen complement regulatory protein, CD59 antigen p18 20, CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344) , CD59 glycoprotein, CD59 molecule, CD59 molecule complement regulatory protein, CD59, Cd59a, Complement regulatory protein, EJ16, EJ30, EL32, FLJ38134, FLJ92039, G344, HRF 20, HRF-20, HRF20, Human leukocyte antigen MIC11, Ly 6 like protein, Lymphocytic antigen CD59/MEM43, MAC inhibitory protein, MAC IP, MAC-inhibitory protein, MAC-IP, MACIF, MACIP, MEM43, MEM43 antigen, Membrane attack complex (MAC) inhibition factor, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, MGC2354, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, p18 20, Protectin, Surface antigen recognized by monoclonal 16.3A5, T cell activating protein

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_000602

Clonality: Polyclonal

Immunogen: Synthetic peptide of human CD59

Clone #:

Conjugation: Unconjugated

Swissprot: P13987

Santa Cruz: sc-7077/sc-7076/sc-28805

Calculated MW: 14 kDa

Observed MW:

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:500-1:2000, IHC 1:100-1:300

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CD59 Polyclonal Antibody DataSheet