CDK5 Polyclonal Antibody | G-AB-10804

CDK5 Polyclonal Antibody | G-AB-10804 | Gentaur Antibodies

Overview: This gene encodes a proline-directed serine/threonine kinase that is a member of the cyclin-dependent kinase family of proteins. Unlike other members of the family, the protein encoded by this gene does not directly control cell cycle regulation. Instead the protein, which is predominantly expressed at high levels in mammalian postmitotic central nervous system neurons, functions in diverse processes such as synaptic plasticity and neuronal migration through phosphorylation of proteins required for cytoskeletal organization, endocytosis and exocytosis, and apoptosis. In humans, an allelic variant of the gene that results in undetectable levels of the protein has been associated with lethal autosomal recessive lissencephaly-7. Alternative splicing results in multiple transcript variants.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Metabolism, Neuroscience

Synonyms: CDK5, LIS7, PSSALRE

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 1020

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human CDK5 (NP_004926.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q00535

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:10-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CDK5 Polyclonal Antibody DataSheet