CDKN2AIP Polyclonal Antibody | G-AB-00608

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CDKN2AIP Polyclonal Antibody | G-AB-00608 | Gentaur Antibodies

Overview: CDKN2AIP (CDKN2A-interacting protein) , also known as CARF, is a 580 amino acid protein that activates p53 via p14 ARF (alternate reading frame) -dependent and independent pathways. CDKN2AIP-dependent activation of p53, a protein that up-regulates growth arrest and apoptosis-related genes in response to stress signals, leads to an enhancement of p53 function. Expression levels of CDKN2AIP and p53 show an inverse relationship that is caused by a negative-feedback control via a proteasome-mediated degradation pathway. CDKN2AIP is expressed ubiquitously across tissue samples and, along with p14 ARF, is localized to the perinucleolar region within the nucleus.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling

Synonyms: Calcium response factor, CARF, CARF, CDKN2A interacting protein, CDKN2A-interacting protein, Cdkn2aip, collaborates/cooperates with ARF (alternate reading frame) protein, Collaborator of ARF, FLJ20036

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC022270

Clonality: Polyclonal

Immunogen: Recombinant protein of human CDKN2AIP

Clone #:

Conjugation: Unconjugated

Swissprot: Q9NXV6

Santa Cruz: sc-161477/sc-161478

Calculated MW:

Observed MW:

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CDKN2AIP Polyclonal Antibody DataSheet