CECR5 Polyclonal Antibody | G-AB-03602

CECR5 Polyclonal Antibody | G-AB-03602 | Gentaur Antibodies

Overview: Adenosine deaminase is an enzyme that is present in most tissues and exists predominantly as a monomer, although in some tissues it is associated with adenosine deaminase-binding protein. Adenosine deaminase degrades extracellular adenosine, which is toxic for lymphocytes. A novel family of growth factors that share sequence similarity to adenosine deaminase has been identified. The cat eye syndrome critical region protein (CECR) family includes CECR1, CECR2, CECR3, CECR4, CECR5, CECR6, CECR7, CECR8 and CECR9. The genes encoding CECR proteins are candidates for Cat Eye Syndrome (CES) , a developmental disorder associated with the duplication of a 2 Mb region of 22q11.2. CES is characterized by the combination of coloboma of the iris and anal atresia with fistula, downslanting palpebral fissures, preauricular Tags &/or pits, frequent occurrence of heart and renal malformations, and normal or near-normal mental development. CECR family members are widely expressed. Specifically, CECR1 has the highest expression in adult heart, lung, lymphoblasts and placenta. CECR2 is also involved in neurulation and chromatin remodeling. Mutations in the CECR2 gene result in neural tube defects.

Category Type: Polyclonal Antibody

Research Areas: Cell Biology

Synonyms: A930002G03Rik, Cat eye syndrome chromosome region, candidate 5, Cat eye syndrome chromosome region, candidate 5 homolog, Cat eye syndrome critical region protein 5, Cecr5, CECR5, MGC25951, OTTMUSP00000025905

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP149061

Clonality: Polyclonal

Immunogen: Synthetic peptide of human CECR5

Clone #:

Conjugation: Unconjugated

Swissprot: Q9BXW7

Santa Cruz:

Calculated MW: 46 kDa

Observed MW: Refer to figures

Concentration: 1.3 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: WB, ELISA

Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CECR5 Polyclonal Antibody DataSheet