CFD Polyclonal Antibody | G-AB-12047

CFD Polyclonal Antibody | G-AB-12047 | Gentaur Antibodies

Overview: This gene encodes a member of the S1, or chymotrypsin, family of serine peptidases. This protease catalyzes the cleavage of factor B, the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine, a cell signaling protein secreted by adipocytes, which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency, which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease.

Category Type: Polyclonal Antibody

Research Areas: Immunology

Synonyms: CFD, ADIPSIN, ADN, DF, PFD

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 1675

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human CFD (NP_001919.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: P00746

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC

Dilution: IHC 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CFD Polyclonal Antibody DataSheet