CFD Polyclonal Antibody | G-AB-12047
- 3 to 5 Working Days
- Human, Mouse
CFD Polyclonal Antibody | G-AB-12047 | Gentaur Antibodies
Overview: This gene encodes a member of the S1, or chymotrypsin, family of serine peptidases. This protease catalyzes the cleavage of factor B, the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine, a cell signaling protein secreted by adipocytes, which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency, which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease.
Category Type: Polyclonal Antibody
Research Areas: Immunology
Synonyms: CFD, ADIPSIN, ADN, DF, PFD
Reactivity: Human, Mouse
Gene ID: 1675
Immunogen: Recombinant fusion protein of human CFD (NP_001919.2) .
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Dilution: IHC 1:50-1:100
Storage: Store at -20°C. Avoid freeze / thaw cycles.