CHAMP1 Polyclonal Antibody | G-AB-07603

CHAMP1 Polyclonal Antibody | G-AB-07603 | Gentaur Antibodies

Overview: CHAMP1 (chromosome alignment maintaining phosphoprotein 1) , also known as ZNF828 or C13orf8, is a 812 amino acid protein containing one C2H2-type zinc finger. CHAMP1 is required for the proper alignment of chromosomes during metaphase, undergoing CDK1-dependent phosphorylation at multiple sites during mitosis. The phosphorylation counteracts the negative chromosomal alignment regulation of the zinc-finger domain of CHAMP1. One region of CHAMP1, the FPE region, is responsible for spindle and kinetochore localization, which is essential for proper chromosome alignment. CHAMP1 interacts with MAD2L2, PGOZ, CBX1, CBX3 and CBX5, and may recruit CENPE and CENPF to the kinetochore. The CHAMP1 gene is located on chromosome 13 and is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat and chicken.

Category Type: Polyclonal Antibody

Research Areas: Epigenetics and Nuclear Signaling

Synonyms: CHAMP1, C13orf8, CAMP, CHAMP, MRD40, ZNF828

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 283489

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human CHAMP1 (NP_115812.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q96JM3

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CHAMP1 Polyclonal Antibody DataSheet