CHD3 Polyclonal Antibody | G-AB-10019

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$218.00 - $465.00
SKU:
G-AB-10019
Availability:
3 to 5 Working Days
Host:
Rabbit
Reactivity:
Human, Mouse, Rat
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CHD3 Polyclonal Antibody | G-AB-10019 | Gentaur Antibodies

Overview: This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Immunology

Synonyms: CHD3, Mi-2a, Mi2-ALPHA, ZFH

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 1107

Accession #:

Clonality:

Immunogen: A synthetic peptide of human CHD3 (NP_001005273.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q12873

Santa Cruz:

Calculated MW: 222 kDa/226 kDa/233 kDa

Observed MW: 280 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:200-1:1000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CHD3 Polyclonal Antibody DataSheet