CHEK1 Polyclonal Antibody | G-AB-11789
Gentaur Antibodies
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Gentaur Antibodies
CHEK1 Polyclonal Antibody | G-AB-11789
- SKU:
- G-AB-11789
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
CHEK1 Polyclonal Antibody | G-AB-11789 | Gentaur Antibodies
Overview: The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Epigenetics and Nuclear Signaling
Synonyms: CHEK1, CHK1
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID: 1111
Accession #:
Clonality:
Immunogen: A synthetic peptide of human CHEK1
Clone #:
Conjugation: Unconjugated
Swissprot: O14757
Santa Cruz:
Calculated MW: 43 kDa/50 kDa/54 kDa
Observed MW: 54 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB, IHC, IF
Dilution: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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