CHRNA4 Polyclonal Antibody | G-AB-09446

CHRNA4 Polyclonal Antibody | G-AB-09446 | Gentaur Antibodies

Overview: This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Alternative splicing results in multiple transcript variants.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Metabolism, Neuroscience

Synonyms: CHRNA4, BFNC, EBN, EBN1, NACHR, NACHRA4, NACRA4

Reactivity: Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 1137

Accession #:

Clonality:

Immunogen: Recombinant protein of human CHRNA4

Clone #:

Conjugation: Unconjugated

Swissprot: P43681

Santa Cruz:

Calculated MW: 60 kDa/69 kDa

Observed MW: 70 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CHRNA4 Polyclonal Antibody DataSheet