CHRNA7 Polyclonal Antibody | G-AB-01353
Gentaur Antibodies
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Gentaur Antibodies
CHRNA7 Polyclonal Antibody | G-AB-01353
- SKU:
- G-AB-01353
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
CHRNA7 Polyclonal Antibody | G-AB-01353 | Gentaur Antibodies
Overview: The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A) . Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Metabolism, Neuroscience
Synonyms: 7nAChR, a7 nicotinic acetylcholine receptor, acetylcholine receptor, neuronal nicotinic, alpha-7 subunit, ACHA7, AChR, Acra7, alpha 7 neuronal nicotinic acetylcholine receptor, alpha-7 nicotinic cholinergic receptor subunit, alpha7, cholinergic receptor, neuronal nicotinic, alpha polypeptide 7, cholinergic receptor, nicotinic, alpha 7 (neuronal) , cholinergic receptor, nicotinic, alpha 7, cholinergic receptor, nicotinic, alpha polypeptide 7, CHRNA7, CHRNA7-2, NACHRA7, neuronal acetylcholine receptor protein, alpha-7 chain, Neuronal acetylcholine receptor subunit alpha-7
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID:
Accession #: NP_683709
Clonality: Polyclonal
Immunogen: Synthetic peptide of human CHRFAM7A
Clone #:
Conjugation: Unconjugated
Swissprot: P36544
Santa Cruz:
Calculated MW: 46 kDa
Observed MW:
Concentration: 0.3 mg/mL
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Affinity purification
Application: WB, IHC, ELISA
Dilution: WB 1:500-1:2000, IHC 1:25-1:100
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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