CISH Polyclonal Antibody | G-AB-08714

CISH Polyclonal Antibody | G-AB-08714 | Gentaur Antibodies

Overview: The protein encoded by this gene contains a SH2 domain and a SOCS box domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS) , also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI) , protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM-CSF and EPO in hematopoietic cells. Proteasome-mediated degradation of this protein has been shown to be involved in the inactivation of the erythropoietin receptor. Multiple transcript variants encoding different isoforms have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Epigenetics and Nuclear Signaling, Signal Transduction

Synonyms: CISH, BACTS2, CIS, CIS-1, G18, SOCS

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 1154

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human CISH (NP_659508.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q9NSE2

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CISH Polyclonal Antibody DataSheet