Cleaved-CASP3 p17 (D175) Polyclonal Antibody | G-AB-05849
Gentaur Antibodies
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Gentaur Antibodies
Cleaved-CASP3 p17 (D175) Polyclonal Antibody | G-AB-05849
- SKU:
- G-AB-05849
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
Cleaved-CASP3 p17 (D175) Polyclonal Antibody | G-AB-05849 | Gentaur Antibodies
Overview: Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly (ADP-ribose) polymerase (PARP) at a '216-Asp-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cell Biology, Metabolism, Neuroscience
Synonyms: A830040C14Rik, Apopain, CASP-3, CASP3, CASP3, Casp3a, Caspase 3, Caspase 3, apoptosis-related cysteine peptidase, Caspase 3, apoptosis-related cysteine protease, Caspase 3, apoptosis-related cysteine protease a, Caspase-3 subunit p12, CC3, CPP-32, CPP32, CPP32B, Cysteine protease CPP32, EC 3.4.22.56, LICE, mldy, OTTHUMP00000165052, OTTHUMP00000165053, OTTHUMP00000165054, PARP cleavage protease, Procaspase3, Protein Yama, SCA 1, SCA-1, SREBP cleavage activity 1, Yama
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID:
Accession #:
Clonality: Polyclonal
Immunogen: Synthesized peptide derived from the Internal region of human Caspase-3 p17
Clone #:
Conjugation: Unconjugated
Swissprot: P42574
Santa Cruz:
Calculated MW: 32 kDa
Observed MW: 20 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification method: Affinity purification
Application: WB, IHC-p, IF, ELISA
Dilution: WB 1:500-2000, IHC 1:50-300, IF 1:50-300
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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