Cleaved-PARP1 (D214) Polyclonal Antibody | G-AB-05852
Gentaur Antibodies
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Gentaur Antibodies
Cleaved-PARP1 (D214) Polyclonal Antibody | G-AB-05852
- SKU:
- G-AB-05852
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
Cleaved-PARP1 (D214) Polyclonal Antibody | G-AB-05852 | Gentaur Antibodies
Overview: This gene encodes a chromatin-associated enzyme, poly (ADP-ribosyl) transferase, which modifies various nuclear proteins by poly (ADP-ribosyl) ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Metabolism
Synonyms: ADP-ribosyltransferase diphtheria toxin-like 1, ADPRT 1, ADPRT, ADPRT1, APOPAIN, ARTD1, NAD (+) ADP-ribosyltransferase 1, PARP, PARP-1, PARP1, PARP1, Poly [ADP-ribose] polymerase 1, Poly ADP ribose polymerase 1, Poly[ADP-ribose] synthase 1, PPOL, SCA1
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Gene ID:
Accession #:
Clonality: Polyclonal
Immunogen: Synthesized peptide derived from the Internal region of human PARP-1
Clone #:
Conjugation: Unconjugated
Swissprot: P09874
Santa Cruz:
Calculated MW: 113 kDa
Observed MW: 24 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification method: Affinity purification
Application: WB, IHC-p, IF, ELISA
Dilution: WB 1:500-2000, IHC 1:50-300, IF 1:50-300
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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