Cleaved-PARP1 (G215) Polyclonal Antibody | G-AB-05851

Cleaved-PARP1 (G215) Polyclonal Antibody | G-AB-05851 | Gentaur Antibodies

Overview: This gene encodes a chromatin-associated enzyme, poly (ADP-ribosyl) transferase, which modifies various nuclear proteins by poly (ADP-ribosyl) ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Metabolism

Synonyms: ADP-ribosyltransferase diphtheria toxin-like 1, ADPRT 1, ADPRT, ADPRT1, APOPAIN, ARTD1, NAD (+) ADP-ribosyltransferase 1, PARP, PARP-1, PARP1, PARP1, Poly [ADP-ribose] polymerase 1, Poly ADP ribose polymerase 1, Poly[ADP-ribose] synthase 1, PPOL, SCA1

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #:

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from the Internal region of human PARP-1

Clone #:

Conjugation: Unconjugated

Swissprot: P09874

Santa Cruz:

Calculated MW: 113 kDa

Observed MW: 89 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

Purification method: Affinity purification

Application: WB, ELISA

Dilution: WB 1:500-1:2000, ELISA 1:5000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Cleaved-PARP1 (G215) Polyclonal Antibody DataSheet