COPS5 Polyclonal Antibody | G-AB-09712

COPS5 Polyclonal Antibody | G-AB-09712 | Gentaur Antibodies

Overview: The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Neuroscience, Signal Transduction

Synonyms: COPS5, CSN5, JAB1, MOV-34, SGN5

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 10987

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human COPS5 (NP_006828.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q92905

Santa Cruz:

Calculated MW: 37 kDa

Observed MW: 37 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC

Dilution: WB 1:500-1:2000 IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

COPS5 Polyclonal Antibody DataSheet