COX11 Polyclonal Antibody | G-AB-01983

COX11 Polyclonal Antibody | G-AB-01983 | Gentaur Antibodies

Overview: Cytochrome c oxidase (COX) , the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be a heme A biosynthetic enzyme involved in COX formation, according to the yeast mutant studies. However, the studies in Rhodobacter sphaeroides suggest that this gene is not required for heme A biosynthesis, but required for stable formation of the Cu (B) and magnesium centers of COX. This human protein is predicted to contain a transmembrane domain localized in the mitochondrial inner membrane. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene has been found on chromosome 6.

Category Type: Polyclonal Antibody

Research Areas:

Synonyms: COX11P

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC005895

Clonality: Polyclonal

Immunogen: Recombinant protein of human COX11

Clone #:

Conjugation: Unconjugated

Swissprot: Q9Y6N1

Santa Cruz: sc-48980/sc-48981/sc-48982/sc-98918

Calculated MW: 31 kDa

Observed MW:

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:1000-1:5000, IHC 1:25-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

COX11 Polyclonal Antibody DataSheet