COX17 Polyclonal Antibody | G-AB-04728

COX17 Polyclonal Antibody | G-AB-04728 | Gentaur Antibodies

Overview: Cytochrome c oxidase (COX) , the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be involved in the recruitment of copper to mitochondria for incorporation into the COX apoenzyme. This protein shares 92% amino acid sequence identity with mouse and rat Cox17 proteins. This gene is no longer considered to be a candidate gene for COX deficiency. A pseudogene COX17P has been found on chromosome 13.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Metabolism, Signal Transduction

Synonyms: COX 17, COX17, COX17 cytochrome c oxidase assembly homolog (S. cerevisiae) , COX17 cytochrome c oxidase assembly homolog, COX17 homolog cytochrome c oxidase assembly protein, COX17, cytochrome c oxidase assembly protein cox17 homolog, Cytochrome c oxidase copper chaperone, Human homolog of yeast mitochondrial copper recruitment, MGC104397, MGC117386, OTTHUMP00000215284, OTTHUMP00000215285

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP005685

Clonality: Polyclonal

Immunogen: Synthetic peptide of human COX17

Clone #:

Conjugation: Unconjugated

Swissprot: Q14061

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1.2 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: IHC, ELISA

Dilution: IHC 1:30-1:150, ELISA 1:2000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

COX17 Polyclonal Antibody DataSheet