COX7A2L Polyclonal Antibody | G-AB-06109

COX7A2L Polyclonal Antibody | G-AB-06109 | Gentaur Antibodies

Overview: Cytochrome c oxidase (COX) , the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen. Several transcript variants, some protein-coding and others non-protein coding, have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Metabolism, Signal Transduction

Synonyms: COX7a related protein, COX7a-related protein, COX7A2L, COX7AR, COX7R, COX7RP, Cytochrome c oxidase subunit 7A-related protein, cytochrome c oxidase subunit 7A-related protein, mitochondrial, Cytochrome c oxidase subunit 7A2 like, cytochrome c oxidase subunit VII-related protein, cytochrome c oxidase subunit VIIa polypeptide 2 like, Cytochrome c oxidase subunit VIIa related protein, mitochondrial, Cytochrome c oxidase subunit VIIa-related protein, EB1, Estrogen receptor binding CpG island, mitochondrial, SIG81

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC007095

Clonality: Polyclonal

Immunogen: Full length fusion protein

Clone #:

Conjugation: Unconjugated

Swissprot: O14548

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 2.5 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: IHC, ELISA

Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

COX7A2L Polyclonal Antibody DataSheet