COX7A2L Polyclonal Antibody | G-AB-12126

COX7A2L Polyclonal Antibody | G-AB-12126 | Gentaur Antibodies

Overview: Cytochrome c oxidase (COX) , the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen. Several transcript variants, some protein-coding and others non-protein coding, have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Metabolism, Signal Transduction

Synonyms: COX7A2L, COX7AR, COX7RP, EB1, SIG81

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 9167

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human COX7A2L (NP_004709.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: O14548

Santa Cruz:

Calculated MW: 12 kDa

Observed MW: 13 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

COX7A2L Polyclonal Antibody DataSheet