CSTB Polyclonal Antibody | G-AB-01659

CSTB Polyclonal Antibody | G-AB-01659 | Gentaur Antibodies

Overview: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins) , type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1) .

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology

Synonyms: CHROW21, CPI B, CPI-B, CST 6, CST6, CSTB, Cystatin B (stefin B) , Cystatin B, Cystatin-B, CYTB, CYTB, EPM1, EPM1A, Liver thiol proteinase inhibitor, PME, Stefin-B, STF B, STFB, ULD

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_000091

Clonality: Polyclonal

Immunogen: Synthetic peptide of human CSTB

Clone #:

Conjugation: Unconjugated

Swissprot: P04080

Santa Cruz: sc-33274/sc-66853

Calculated MW:

Observed MW:

Concentration: 0.9 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CSTB Polyclonal Antibody DataSheet