CXCR3 Polyclonal Antibody | G-AB-07583

CXCR3 Polyclonal Antibody | G-AB-07583 | Gentaur Antibodies

Overview: This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g) , CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant) . Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716) .

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Immunology, Signal Transduction

Synonyms: CXCR3, CD182, CD183, CKR-L2, CMKAR3, GPR9, IP10-R, Mig-R, MigR

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 2833

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human CXCR3 (NP_001495.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P49682

Santa Cruz:

Calculated MW: 28 kDa/40 kDa/45 kDa

Observed MW: 41 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CXCR3 Polyclonal Antibody DataSheet