CYP2E1 Polyclonal Antibody | G-AB-09982

CYP2E1 Polyclonal Antibody | G-AB-09982 | Gentaur Antibodies

Overview: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Metabolism, Signal Transduction

Synonyms: CYP2E1, CPE1, CYP2E, P450-J, P450C2E

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 1571

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human CYP2E1 (NP_000764.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P05181

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC, IF

Dilution: IHC 1:50-1:100 IF 1:20-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CYP2E1 Polyclonal Antibody DataSheet