CYP46A1 Polyclonal Antibody | G-AB-12278
- 3 to 5 Working Days
- Human, Mouse, Rat
CYP46A1 Polyclonal Antibody | G-AB-12278 | Gentaur Antibodies
Overview: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Metabolism, Neuroscience, Signal Transduction
Synonyms: CYP46A1, CP46, CYP46
Reactivity: Human, Mouse, Rat
Gene ID: 10858
Immunogen: Recombinant fusion protein of human CYP46A1 (NP_006659.1) .
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Dilution: IHC 1:50-1:100
Storage: Store at -20°C. Avoid freeze / thaw cycles.