DAZL Polyclonal Antibody | G-AB-07490

DAZL Polyclonal Antibody | G-AB-07490 | Gentaur Antibodies

Overview: The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. Two transcript variants encoding different isoforms have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas:

Synonyms: DAZL, DAZH, DAZL1, DAZLA, SPGYLA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 1618

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human DAZL (NP_001342.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q92904

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

DAZL Polyclonal Antibody DataSheet