DCTN2 Polyclonal Antibody | G-AB-10010

DCTN2 Polyclonal Antibody | G-AB-10010 | Gentaur Antibodies

Overview: This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cell Biology, Signal Transduction

Synonyms: DCTN2, DCTN50, DYNAMITIN, HEL-S-77, RBP50

Reactivity: Human, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 10540

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human DCTN2 (NP_006391.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q13561

Santa Cruz:

Calculated MW: 44 kDa

Observed MW: 44 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC, IF

Dilution: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:20-1:50

Storage: Store at -20°C. Avoid freeze / thaw cycles.

DCTN2 Polyclonal Antibody DataSheet