DDIT3 / CHOP Polyclonal Antibody | G-AB-11140
- 3 to 5 Working Days
- Human, Mouse, Rat
DDIT3 / CHOP Polyclonal Antibody | G-AB-11140 | Gentaur Antibodies
Overview: This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein) , and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Metabolism, Developmental Biology, Stem Cells
Synonyms: DDIT3, CEBPZ, CHOP, CHOP-10, CHOP10, GADD153, C/EBPzeta, DDIT3 / CHOP
Reactivity: Human, Mouse, Rat
Gene ID: 1649
Immunogen: Recombinant protein of human DDIT3 / CHOP
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Dilution: IF 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.