DENND1B Polyclonal Antibody | G-AB-04123

DENND1B Polyclonal Antibody | G-AB-04123 | Gentaur Antibodies

Overview: Clathrin (see MIM 118955) -mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024) . Thus, connecdenns link RAB35 activation with the clathrin machinery.

Category Type: Polyclonal Antibody

Research Areas: Cell Biology

Synonyms: C1ORF18, C1orf218, Chromosome 1 open reading frame 218, Connecdenn 2, DEN1B, DENN domain containing protein 1B, DENN domain-containing protein 1B, DENN MADD domain containing 1B, DENND1B, DKFZp547O0715, FAM31B, Family with sequence similarity 31 member B, FLJ20054, FLJ21179, FLJ33888, MGC103810, MGC27044, Protein FAM31B, RP11 53I24.2

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC063877

Clonality: Polyclonal

Immunogen: Fusion protein of human DENND1B

Clone #:

Conjugation: Unconjugated

Swissprot: Q6P3S1

Santa Cruz:

Calculated MW: 86 kDa

Observed MW: Refer to figures

Concentration: 0.54 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: WB, ELISA

Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

DENND1B Polyclonal Antibody DataSheet