DHCR24 Polyclonal Antibody | G-AB-02666

DHCR24 Polyclonal Antibody | G-AB-02666 | Gentaur Antibodies

Overview: This gene encodes a flavin adenine dinucleotide (FAD) -dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Cardiovascular, Metabolism, Neuroscience

Synonyms: 24 dehydrocholesterol reductase, 24-dehydrocholesterol reductase, 3 beta hydroxysterol delta 24 reductase, 3-beta-hydroxysterol delta-24-reductase, DCE, Delta (24) -sterol reductase, Desmosterol to cholesterol enzyme, DHC24, Dhcr24, Diminuto dwarf1 homolog, Diminuto/dwarf1 homolog, KIAA0018, Nbla03646, Seladin-1, SELADIN1, Selective AD indicator 1, Selective Alzheimer's Disease Indicator 1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC004375

Clonality: Polyclonal

Immunogen: Recombinant protein of human DHCR24

Clone #:

Conjugation: Unconjugated

Swissprot: Q15392

Santa Cruz: sc-48475/sc-48476/sc-48477

Calculated MW:

Observed MW:

Concentration: 0.7 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:30-1:150

Storage: Store at -20°C. Avoid freeze / thaw cycles.

DHCR24 Polyclonal Antibody DataSheet