DHH Polyclonal Antibody | G-AB-08090

DHH Polyclonal Antibody | G-AB-08090 | Gentaur Antibodies

Overview: This gene encodes a member of the hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development.

Category Type: Polyclonal Antibody

Research Areas: Stem Cells

Synonyms: DHH, GDXYM, HHG-3, SRXY7

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 50846

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human DHH (NP_066382.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: O43323

Santa Cruz:

Calculated MW: 43 kDa

Observed MW: 44 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

DHH Polyclonal Antibody DataSheet