DMBT1 Polyclonal Antibody | G-AB-12685
- 3 to 5 Working Days
- Human, Mouse, Rat
DMBT1 Polyclonal Antibody | G-AB-12685 | Gentaur Antibodies
Overview: Loss of sequences from human chromosome 10q has been associated with the progression of human cancers. The gene DMBT1 was originally isolated based on its deletion in a medulloblastoma cell line. DMBT1 is expressed with transcripts of 6.0, 7.5, and 8.0 kb in fetal lung and with one transcript of 8.0 kb in adult lung, although the 7.5 kb transcript has not been characterized. The DMBT1 protein is a glycoprotein containing multiple scavenger receptor cysteine-rich (SRCR) domains separated by SRCR-interspersed domains (SID) . Transcript variant 2 (8.0 kb) has been shown to bind surfactant protein D independently of carbohydrate recognition. This indicates that DMBT1 may not be a classical tumor suppressor gene, but rather play a role in the interaction of tumor cells and the immune system.
Category Type: Polyclonal Antibody
Research Areas: Signal Transduction
Synonyms: Apactin, CRP, Crpd, DBMT1, Deleted in malignant brain tumors 1 protein, DMBT1, DMBT1 prototype precursor, Ebnerin, FLJ61058, Glycoprotein 300, Glycoprotein 340, GP340, Gp340 variant protein, GP340, Hensin, MGC164738, Muclin, p80, Pancrin, SAG, Salivary agglutinin, Surfactant pulmonary associated D binding protein, Vomeroglandin
Reactivity: Human, Mouse, Rat
Gene ID: 170568
Immunogen: Recombinant Rat Deleted in malignant brain tumors 1 protein
Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3.
Purification method: Antigen Affinity Purification
Dilution: IHC 1:200-1:400
Storage: Store at -20℃. Avoid freeze / thaw cycles.