DNAJA4 Polyclonal Antibody | G-AB-04593

DNAJA4 Polyclonal Antibody | G-AB-04593 | Gentaur Antibodies

Overview: The DnaJ family is one of the largest of all the chaperone families and has evolved with diverse cellular localization and functions. The presence of the J domain defines a protein as a member of the DnaJ family. DnaJ heat shock induced proteins are from the bacterium Escherichia coli and are under the control of the htpR regulatory protein. The DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis. The proteins contain cysteine rich regions that are composed of zinc fingers that form a peptide binding domain responsible for the chaperone function. DnaJ proteins are important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis. DnaJA4 (DnaJ homolog subfamily A member 4) is a SREBP-regulated chaperone that is thought to regulate the cholesterol biosynthesis pathway.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Metabolism, Signal Transduction

Synonyms: DnaJ (Hsp40) homolog subfamily A member 4, DnaJ (Hsp40) homolog, subfamily A, member4, DNAJ A4, DnaJ heat shock protein family (Hsp40) member A4, DnaJ homolog subfamily A member 4, DNAJA 4, DNAJA4, DNJA4, MST104, MSTP104, PRO1472

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC031044

Clonality: Polyclonal

Immunogen: Fusion protein of human DNAJA4

Clone #:

Conjugation: Unconjugated

Swissprot: Q8WW22

Santa Cruz:

Calculated MW: 45 kDa

Observed MW: Refer to figures

Concentration: 0.96 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:500-1:2000, IHC 1:50-1:200, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

DNAJA4 Polyclonal Antibody DataSheet