DSP Polyclonal Antibody | G-AB-01257
Gentaur Antibodies
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Gentaur Antibodies
DSP Polyclonal Antibody | G-AB-01257
- SKU:
- G-AB-01257
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
DSP Polyclonal Antibody | G-AB-01257 | Gentaur Antibodies
Overview: Desmosomes are intercellular junctions that tightly link adjacent cells. Desmoplakin is an obligate component of functional desmosomes that anchors intermediate filaments to desmosomal plaques. The N-terminus of desmoplakin is required for localization to the desmosome and interacts with the N-terminal region of plakophilin 1 and plakoglobin. The C-terminus of desmoplakin binds with intermediate filaments. In the mid-region of desmoplakin, a coiled-coiled rod domain is responsible for homodimerization. Mutations in this gene are the cause of several cardiomyopathies and keratodermas as well as the autoimmune disease paraneoplastic pemphigus.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Signal Transduction
Synonyms: 250/210 kDa paraneoplastic pemphigus antigen, DCWHKTA, Desmoplakin (DPI DPII) , Desmoplakin, Desmoplakin I, Desmoplakin II, DESP, DP, DP I, DP II, DPI, DPII, DSP, KPPS2, PPKS 2, PPKS2
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Gene ID:
Accession #: NP_004406
Clonality: Polyclonal
Immunogen: Synthetic peptide of human DSP
Clone #:
Conjugation: Unconjugated
Swissprot: P15924
Santa Cruz: sc-18083/sc-18086/sc-18082/sc-33555
Calculated MW:
Observed MW:
Concentration: 0.5 mg/mL
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Affinity purification
Application: IHC, ELISA
Dilution: IHC 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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