DUSP11 Polyclonal Antibody | G-AB-03440

DUSP11 Polyclonal Antibody | G-AB-03440 | Gentaur Antibodies

Overview: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38) , which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is localized to the nucleus and binds directly to RNA and splicing factors, and thus it is suggested to participate in nuclear mRNA metabolism.

Category Type: Polyclonal Antibody

Research Areas: Epigenetics and Nuclear Signaling, Signal Transduction

Synonyms: Dual specificity phosphatase 11, Dual specificity protein phosphatase 11, DUS11, DUSP11, Phosphatase that interacts with RNA/RNP complex 1, PIR1, RNA/RNP complex 1 interacting, RNA/RNP complex interacting phosphatase, RNA/RNP complex-1-interacting phosphatase, RNA/RNP complex1 intereracting phosphatase, Serine/threonine specific protein phosphatase

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC000346

Clonality: Polyclonal

Immunogen: Full length fusion protein

Clone #:

Conjugation: Unconjugated

Swissprot: O75319

Santa Cruz: sc-47919/sc-47918/sc-47922/sc-47921

Calculated MW:

Observed MW:

Concentration: 1.5 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:30-150, ELISA 1:2000-10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

DUSP11 Polyclonal Antibody DataSheet