EDARADD Polyclonal Antibody | G-AB-06205

EDARADD Polyclonal Antibody | G-AB-06205 | Gentaur Antibodies

Overview: This gene was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Category Type: Polyclonal Antibody

Research Areas: Epigenetics and Nuclear Signaling, Developmental biology, Signal Transduction

Synonyms: Cr, Crinkled homolog, ectodysplasia A receptor associated death domain, Ectodysplasin-A receptor-associated adapter protein, ED3, EDA3, EDAD, EDAR associated death domain, EDAR-associated death domain protein, EDARADD, Protein crinkled homolog

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC128082

Clonality: Polyclonal

Immunogen: Full length fusion protein

Clone #:

Conjugation: Unconjugated

Swissprot: Q8WWZ3

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 0.9 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: IHC, ELISA

Dilution: IHC 1:35-1:200, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

EDARADD Polyclonal Antibody DataSheet