EDN3 Polyclonal Antibody | G-AB-00977

EDN3 Polyclonal Antibody | G-AB-00977 | Gentaur Antibodies

Overview: The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB) . The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS) , which are congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Neuroscience, Signal Transduction

Synonyms: EDN3, EDN3, Endothelin-3, ET 3, ET-3, PPET3, Preproendothelin 3, Preproendothelin-3

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC008876

Clonality: Polyclonal

Immunogen: Recombinant protein of human EDN3

Clone #:

Conjugation: Unconjugated

Swissprot: P14138

Santa Cruz: sc-21628

Calculated MW:

Observed MW:

Concentration: 0.8 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

EDN3 Polyclonal Antibody DataSheet