EGFR Polyclonal Antibody | G-AB-00242

EGFR Polyclonal Antibody | G-AB-00242 | Gentaur Antibodies

Overview: EGFR, also named as ERBB1, is a cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. The gene resides on chromosome 7p12, encoding a 170 kDa membrane-associated glycoprotein. Recent studies have shown EGFR plays a critical role in cancer development and progression, including cell proliferation, apoptosis, angiogenesis, and metastatic spread. Mutations in this gene are associated with lung cancer.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Signal Transduction

Synonyms: Cell growth inhibiting protein 40, Cell proliferation inducing protein 61, EGF R, EGFR, Epidermal growth factor receptor (avian erythroblastic leukemia viral (v erb b) oncogene homolog) , Epidermal growth factor receptor, erb-b2 receptor tyrosine kinase 1, ERBB, ERBB1, Errp, HER1, mENA, NISBD2, SA7, wa2, Wa5

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #:

Clonality: Polyclonal

Immunogen: Recombinant Human Epidermal growth factor receptor protein

Clone #:

Conjugation: Unconjugated

Swissprot: P00533

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 0.57 mg/mL

Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.

Purification method: Antigen Affinity Purification

Application: IHC, IF

Dilution: IHC 1:100-1:200 IF 1:100-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

EGFR Polyclonal Antibody DataSheet