EGFR Polyclonal Antibody | G-AB-05202

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$156.96 - $334.80
SKU:
G-AB-05202
Availability:
3 to 5 Working Days
Host:
Rabbit
Reactivity:
Human
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EGFR Polyclonal Antibody | G-AB-05202 | Gentaur Antibodies

Overview: EGFR, also named as ERBB1, is a cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. The gene resides on chromosome 7p12, encoding a 170 kDa membrane-associated glycoprotein. Recent studies have shown EGFR plays a critical role in cancer development and progression, including cell proliferation, apoptosis, angiogenesis, and metastatic spread. Mutations in this gene are associated with lung cancer.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Signal Transduction

Synonyms: Avian erythroblastic leukemia viral (v erb b) oncogene homolog, Cell growth inhibiting protein 40, Cell proliferation inducing protein 61, EGF R, EGFR, EGFR, Epidermal growth factor receptor (avian erythroblastic leukemia viral (v erb b) oncogene homolog) , Epidermal growth factor receptor (erythroblastic leukemia viral (v erb b) oncogene homolog avian) , Epidermal growth factor receptor, erb-b2 receptor tyrosine kinase 1, ERBB, ERBB1, Errp, HER1, mENA, NISBD2, Oncogen ERBB, PIG61, Proto-oncogene c-ErbB-1, Receptor tyrosine protein kinase ErbB 1, Receptor tyrosine-protein kinase ErbB-1, SA7, Species antigen 7, Urogastrone, v-erb-b Avian erythroblastic leukemia viral oncogen homolog, wa2, Wa5

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #:

Clonality: Polyclonal

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse EGFR

Clone #:

Conjugation: Unconjugated

Swissprot: P00533, Q01279

Santa Cruz:

Calculated MW: 134 kDa

Observed MW: 175 kDa

Concentration: 110 μg/mL

Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

EGFR Polyclonal Antibody DataSheet