EGLN1 Polyclonal Antibody | G-AB-10031
Gentaur Antibodies
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Gentaur Antibodies
EGLN1 Polyclonal Antibody | G-AB-10031
- SKU:
- G-AB-10031
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human
EGLN1 Polyclonal Antibody | G-AB-10031 | Gentaur Antibodies
Overview: The protein encoded by this gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex. Mutations in this gene are associated with erythrocytosis familial type 3 (ECYT3) .
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism
Synonyms: EGLN1, C1orf12, ECYT3, HALAH, HIF-PH2, HIFPH2, HPH-2, HPH2, PHD2, SM20, ZMYND6
Reactivity: Human
Host: Rabbit
Isotype: IgG
Gene ID: 54583
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human EGLN1 (NP_071334.1) .
Clone #:
Conjugation: Unconjugated
Swissprot: Q9GZT9
Santa Cruz:
Calculated MW:
Observed MW:
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: IF
Dilution: IF 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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