EIF3H Polyclonal Antibody | G-AB-08193

EIF3H Polyclonal Antibody | G-AB-08193 | Gentaur Antibodies

Overview: Eukaryotic translation initiation factor 3 subunit His aproteinthat in humans is encoded by theEIF3Hgene. Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP: methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC) . The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.

Category Type: Polyclonal Antibody

Research Areas: Epigenetics and Nuclear Signaling

Synonyms: EIF3H, EIF3S3, eIF3-gamma, eIF3-p40

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 8667

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human EIF3H (NP_003747.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: O15372

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

EIF3H Polyclonal Antibody DataSheet